Turpeinen, Miia: search on Z-Library

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1

Toxicity of Carboxylic Acid-Containing Drugs: The Role of Acyl Migration and CoA Conjugation Investigated

Lassila, Toni, Hokkanen, Juho, Aatsinki, Sanna-Mari, Mattila, Sampo, Turpeinen, Miia, Tolonen, Ari

Journal:

Chemical Research in Toxicology

Year:

2015

Language:

english

File:

PDF, 1.55 MB

english, 2015

2

CYP-associated drugâdrug interactions: A mission accomplished?

Pelkonen, Olavi, Hakkola, Jukka, Hukkanen, Janne, Turpeinen, Miia

Journal:

Archives of Toxicology

Year:

2020

File:

PDF, 434 KB

2020

3

From known knowns to known unknowns: predicting in vivo drug metabolites

Pelkonen, Olavi, Tolonen, Ari, Korjamo, Timo, Turpeinen, Miia, Raunio, Hannu

Journal:

Year:

2009

Language:

english

File:

PDF, 802 KB

english, 2009

4

Transfer of repaglinide in the dually perfused human placenta and the role of organic anion transporting polypeptides (OATPs)

Kristiina Tertti, Aleksanteri Petsalo, Mikko Niemi, Ulla Ekblad, Ari Tolonen, Tapani Rönnemaa, Miia Turpeinen, Tuija Heikkinen, Kari Laine

Journal:

European Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 375 KB

english, 2011

5

Metabolism of hyperforin, the active constituent of St. John's wort, in human liver microsomes

Juho Hokkanen, Ari Tolonen, Sampo Mattila, Miia Turpeinen

Journal:

European Journal of Pharmaceutical Sciences

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

6

Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo

Turpeinen, Miia, Uusitalo, Jouko, Lehtinen, Terhi, Kailajärvi, Marita, Pelkonen, Olavi, Vuorinen, Jouni, Tapanainen, Pasi, Stjernschantz, Camilla, Lammintausta, Risto, Scheinin, Mika

Journal:

International Journal of Molecular Sciences

Year:

2013

Language:

english

File:

PDF, 664 KB

english, 2013

7

Discovery of substituted sulfonamides and thiazolidin-4-one derivatives as agonists of human constitutive androstane receptor

Jenni Küblbeck, Johanna Jyrkkärinne, Antti Poso, Miia Turpeinen, Wolfgang Sippl, Paavo Honkakoski, Björn Windshügel

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 742 KB

english, 2008

8

Estrogen receptor alpha genotype confers interindividual variability of response to estrogen and testosterone in mesenchymal-stem-cell-derived osteoblasts

Hannu-Ville Leskelä, Anu Olkku, Siri Lehtonen, Anitta Mahonen, Jussi Koivunen, Miia Turpeinen, Jouko Uusitalo, Olavi Pelkonen, Lauri Kangas, Katri Selander, Petri Lehenkari

Journal:

Year:

2006

Language:

english

File:

PDF, 660 KB

english, 2006

9

Functional expression, inhibition and induction of CYP enzymes in HepaRG cells

Miia Turpeinen, Ari Tolonen, Christophe Chesne, André Guillouzo, Jouko Uusitalo, Olavi Pelkonen

Journal:

Toxicology in Vitro

Year:

2009

Language:

english

File:

PDF, 278 KB

english, 2009

10

Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver

Klein, Kathrin, Winter, Stefan, Turpeinen, Miia, Schwab, Matthias, Zanger, Ulrich M.

Journal:

Frontiers in Pharmacology

Year:

2010

Language:

english

File:

PDF, 4.54 MB

english, 2010

11

Identification of bupropion urinary metabolites by liquid chromatography/mass spectrometry

Aleksanteri Petsalo, Miia Turpeinen, Ari Tolonen

Journal:

Rapid Communications in Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 301 KB

english, 2007

12

Prediction of Drug Metabolism and Interactions on the Basis of in vitro Investigations

Olavi Pelkonen, Miia Turpeinen, Jouko Uusitalo, Arja Rautio, Hannu Raunio

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2005

Language:

english

File:

PDF, 90 KB

english, 2005

13

Cytochrome P450 (CYP) inhibition screening: Comparison of three tests

Miia Turpeinen, Laura E. Korhonen, Ari Tolonen, Jouko Uusitalo, Risto Juvonen, Hannu Raunio, Olavi Pelkonen

Journal:

European Journal of Pharmaceutical Sciences

Year:

2006

Language:

english

File:

PDF, 240 KB

english, 2006

14

Glutathione trapping of reactive drug metabolites produced by biomimetic metalloporphyrin catalysts

Lassila, Toni, Mattila, Sampo, Turpeinen, Miia, Tolonen, Ari

Journal:

Rapid Communications in Mass Spectrometry

Year:

2015

Language:

english

File:

PDF, 313 KB

english, 2015

15

In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies

Ari Tolonen, Aleksanteri Petsalo, Miia Turpeinen, Jouko Uusitalo, Olavi Pelkonen

Journal:

Journal of Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 510 KB

english, 2007

16

Corrigendum to “Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay” [Eur. J. Pharm. Sci. 24 (2005) 123–132]

Miia Turpeinen, Jouko Uusitalo, Jorma Jalonen, Olavi Pelkonen

Journal:

European Journal of Pharmaceutical Sciences

Year:

2005

File:

PDF, 32 KB

2005

17

Hospitalizations Due to Adverse Drug Events in the Elderly—A Retrospective Register Study

Laatikainen, Outi, Sneck, Sami, Bloigu, Risto, Lahtinen, Minna, Lauri, Timo, Turpeinen, Miia

Journal:

Frontiers in Pharmacology

Year:

2016

Language:

english

File:

PDF, 893 KB

english, 2016

18

Comparison of anti-p53 antibodies in immunoblotting

Miia Turpeinen, Raisa Serpi, Mika Rahkolin, Kirsi Vähäkangas

Journal:

Biochemical and Biophysical Research Communications

Year:

2002

Language:

english

File:

PDF, 183 KB

english, 2002

19

Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene

Lehtinen, Terhi, Tolonen, Ari, Turpeinen, Miia, Uusitalo, Jouko, Vuorinen, Jouni, Lammintausta, Risto, Pelkonen, Olavi, Scheinin, Mika

Journal:

Biopharmaceutics & Drug Disposition

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

20

PharmGKB summary

Sangkuhl, Katrin, Stingl, Julia C., Turpeinen, Miia, Altman, Russ B., Klein, Teri E.

Journal:

Pharmacogenetics and Genomics

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

21

The Risks and Outcomes Resulting From Medication Errors Reported in the Finnish Tertiary Care Units:

Laatikainen, Outi, Sneck, Sami, Turpeinen, Miia

Journal:

Frontiers in Pharmacology

Year:

2020

Language:

english

File:

PDF, 1.69 MB

english, 2020

22

Functional pharmacogenetics/genomics of human cytochromes P450 involved in drug biotransformation

Ulrich M. Zanger, Miia Turpeinen, Kathrin Klein, Matthias Schwab

Journal:

Analytical and Bioanalytical Chemistry

Year:

2008

Language:

english

File:

PDF, 334 KB

english, 2008

23

Tandem mass spectrometric analysis of S- and N-linked glutathione conjugates of pulegone and menthofuran and identification of P450 enzymes mediating their formation

Lassila, Toni, Mattila, Sampo, Turpeinen, Miia, Pelkonen, Olavi, Tolonen, Ari

Journal:

Rapid Communications in Mass Spectrometry

Year:

2016

Language:

english

File:

PDF, 1.58 MB

english, 2016

24

Analysis of nine drugs and their cytochrome P450-specific probe metabolites from urine by liquid chromatography–tandem mass spectrometry utilizing sub 2 μm particle size column

Aleksanteri Petsalo, Miia Turpeinen, Olavi Pelkonen, Ari Tolonen

Journal:

Journal of Chromatography A

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

25

Three-dimensional quantitative structure–activity relationship (3D-QSAR) analysis of CYP2B6 enzyme

Hannu Raunio, Laura Korhonen, Miia Turpeinen, Minna Rahnasto, Carsten Wittekindt, Antti Poso, Risto Juvonen

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

26

Glutathione trapping of reactive drug metabolites produced by biomimetic metalloporphyrin catalysts

Lassila, Toni, Mattila, Sampo, Turpeinen, Miia, Tolonen, Ari

Journal:

Rapid Communications in Mass Spectrometry

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

27

Effect of Caffeine Intake 12 or 24 Hours Prior to Melatonin Intake and CYP1A2*1F Polymorphism on CYP1A2 Phenotyping by Melatonin

Sebastian Härtter, Tuomas Korhonen, Stefan Lundgren, Anders Rane, Ari Tolonen, Miia Turpeinen, Kari Laine

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2006

Language:

english

File:

PDF, 95 KB

english, 2006

28

Ospemifene metabolism in humans in vitro and in vivo: metabolite identification, quantitation, and CYP assignment of major hydroxylations

Tolonen, Ari, Koskimies, Pasi, Turpeinen, Miia, Uusitalo, Jouko, Lammintausta, Risto, Pelkonen, Olavi

Journal:

Drug Metabolism and Drug Interactions

Year:

2013

Language:

english

File:

PDF, 444 KB

english, 2013

29

Formation of GSH-trapped reactive metabolites in human liver microsomes, S9 fraction, HepaRG-cells, and human hepatocytes

Lassila, Toni, Rousu, Timo, Mattila, Sampo, Chesné, Christophe, Pelkonen, Olavi, Turpeinen, Miia, Tolonen, Ari

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2015

Language:

english

File:

PDF, 1005 KB

english, 2015

30

Metabolic and Efflux Properties of Caco-2 Cells Stably Transfected with Nuclear Receptors

Timo Korjamo, Jukka Mönkkönen, Jouko Uusitalo, Miia Turpeinen, Olavi Pelkonen, Paavo Honkakoski

Journal:

Pharmaceutical Research

Year:

2006

Language:

english

File:

PDF, 439 KB

english, 2006

31

Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone

Tuomas Korhonen, Miia Turpeinen, Ari Tolonen, Kari Laine, Olavi Pelkonen

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2008

Language:

english

File:

PDF, 328 KB

english, 2008

32

An evaluation of the cytochrome P450 inhibition potential of selected pesticides in human hepatic microsomes

Abass, Khaled, Turpeinen, Miia, Pelkonen, Olavi

Journal:

Journal of Environmental Science and Health Part B

Year:

2009

Language:

english

File:

PDF, 744 KB

english, 2009

33

Preservation, induction or incorporation of metabolism into the in vitro cellular system − Views to current opportunities and limitations

Pelkonen, Olavi, Turpeinen, Miia, Hakkola, Jukka, Abass, Khaled, Pasanen, Markku, Raunio, Hannu, Vähäkangas, Kirsi

Journal:

Toxicology in Vitro

Year:

2013

Language:

english

File:

PDF, 308 KB

english, 2013

34

Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8

Thomas, Maria, Winter, Stefan, Klumpp, Britta, Turpeinen, Miia, Klein, Kathrin, Schwab, Matthias, Zanger, Ulrich M.

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.66 MB

english, 2015

35

Quantitative analysis of 4β- and 4α‑hydroxycholesterol in human plasma and serum by UHPLC/ESI-HR-MS

Hautajärvi, Heidi, Hukkanen, Janne, Turpeinen, Miia, Mattila, Sampo, Tolonen, Ari

Journal:

Journal of Chromatography B

Year:

2018

Language:

english

File:

PDF, 1.07 MB

english, 2018

36

Cytochrome P450 2B6: function, genetics, and clinical relevance

Turpeinen, Miia, Zanger, Ulrich M.

Journal:

Drug Metabolism and Drug Interactions

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

37

Oral diabetes medications other than dipeptidyl peptidase 4 inhibitors are not associated with bullous pemphigoid: A Finnish nationwide case-control study

Varpuluoma, Outi, Försti, Anna-Kaisa, Jokelainen, Jari, Turpeinen, Miia, Timonen, Markku, Tasanen, Kaisa, Huilaja, Laura

Journal:

Journal of the American Academy of Dermatology

Year:

2018

Language:

english

File:

PDF, 252 KB

english, 2018

38

The Effect of Oral Contraceptives on the Pharmacokinetics of Melatonin in Healthy Subjects With CYP1A2 g.-163C>A Polymorphism

Hilli, Johanna, Korhonen, Tuomas, Turpeinen, Miia, Hokkanen, Juho, Mattila, Sampo, Laine, Kari

Journal:

Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 134 KB

english, 2008

39

Vildagliptin significantly increases the risk of bullous pemphigoid: A Finnish nationwide registry study

Varpuluoma, Outi, Försti, Anna-Kaisa, Jokelainen, Jari, Turpeinen, Miia, Timonen, Markku, Huilaja, Laura, Tasanen, Kaisa

Journal:

The Journal of Investigative Dermatology

Year:

2018

Language:

english

File:

PDF, 353 KB

english, 2018

40

Inhibition and induction of CYP enzymes in humans: an update

Hakkola, Jukka, Hukkanen, Janne, Turpeinen, Miia, Pelkonen, Olavi

Journal:

Archives of Toxicology

Year:

2020

File:

PDF, 1.64 MB

2020

41

Inhibition and induction of human cytochrome P450 enzymes: current status

Olavi Pelkonen, Miia Turpeinen, Jukka Hakkola, Paavo Honkakoski, Janne Hukkanen, Hannu Raunio

Journal:

Archives of Toxicology

Year:

2008

Language:

english

File:

PDF, 790 KB

english, 2008

42

Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay

Miia Turpeinen, Uusitalo Jouko, Jalonen Jorma, Pelkonen Olavi

Journal:

European Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 274 KB

english, 2005

43

Effect of renal impairment on the pharmacokinetics of bupropion and its metabolites

Miia Turpeinen, Niina Koivuviita, Ari Tolonen, Petri Reponen, Stefan Lundgren, Jouko Miettunen, Kaj Metsärinne, Anders Rane, Olavi Pelkonen, Kari Laine

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 162 KB

english, 2007

44

Pharmacogenomics of human liver cytochrome P450 oxidoreductase: multifactorial analysis and impact on microsomal drug oxidation

Gomes, Ana M, Winter, Stefan, Klein, Kathrin, Turpeinen, Miia, Schaeffeler, Elke, Schwab, Matthias, Zanger, Ulrich M

Journal:

Pharmacogenomics

Year:

2009

Language:

english

File:

PDF, 754 KB

english, 2009

45

Metabolism of Oxycodone in Human Hepatocytes from Different Age Groups and Prediction of Hepatic Plasma Clearance

Korjamo, Timo, Tolonen, Ari, Ranta, Veli-Pekka, Turpeinen, Miia, Kokki, Hannu

Journal:

Frontiers in Pharmacology

Year:

2012

Language:

english

File:

PDF, 514 KB

english, 2012

46

Effects of Selective Serotonin Reuptake Inhibitors on Timolol Metabolism in Human Liver Microsomes and Cryo-Preserved Hepatocytes

Marjo Volotinen, Timo Korjamo, Ari Tolonen, Miia Turpeinen, Olavi Pelkonen, Jukka Hakkola, Jukka Mäenpää

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

2010

Language:

english

File:

PDF, 209 KB

english, 2010

47

Liquid chromatography–mass spectrometry in in vitro drug metabolite screening

Ari Tolonen, Miia Turpeinen, Olavi Pelkonen

Journal:

Drug Discovery Today

Year:

2009

Language:

english

File:

PDF, 1.13 MB

english, 2009

48

SingleâArm Clinical Trials as Pivotal Evidence for Cancer Drug Approval: a Retrospective Cohort Study of Centralised European Marketing Authorizations between 2010â2019

Tenhunen, Olli, Lasch, Florian, Pean, Elias, Schiel, Anja, Turpeinen, Miia

Journal:

Clinical Pharmacology & Therapeutics

Year:

2020

File:

PDF, 8.49 MB

2020

49

Stability of sufentanil and levobupivacaine solutions and a mixture in a 0.9% sodium chloride infusion stored in polypropylene syringes

Annaliisa Jäppinen, Miia Turpeinen, Hannu Kokki, Anu Rasi, Tarja Ojanen, Olavi Pelkonen, Toivo Naaranlahti

Journal:

European Journal of Pharmaceutical Sciences

Year:

2003

Language:

english

File:

PDF, 119 KB

english, 2003

50

A simple method for differentiation of monoisotopic drug metabolites with hydrogen–deuterium exchange liquid chromatography/electrospray mass spectrometry

Ari Tolonen, Miia Turpeinen, Jouko Uusitalo, Olavi Pelkonen

Journal:

European Journal of Pharmaceutical Sciences

Year:

2005

Language:

english

File:

PDF, 328 KB

english, 2005

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